北 京 化 工 大 学
《有机化学实验A》(II)教学大纲
一、课程基本信息
课程代码 （已开设课程填写） | CHM13101L | ||||||||
课程信息 （仅新开课程填写） | 所属 学科 | 化学 | 知识 领域 | 有机化学 | |||||
课程层次 | □本科生基础课程(通识教育及公共基础) □本科生中级课程(一级学科基础) □本科生高级课程(二级学科基础) □本科生深度课程(学科方向及特色) | ||||||||
总学时 | 48 | 学分 | 1.5 | 理论学时 | 实验学时 | 48 | 上机学时 | ||
课程中文名称 | 有机化学实验A（II） | ||||||||
课程英文名称 | Experiments of Organic Chemistry A (II) | ||||||||
适用专业 | 应用化学专业，理科实验班 | ||||||||
开课学期 | |||||||||
预修课程（名称） | 《无机化学》 《分析化学》 | ||||||||
并修课程（名称） | 《有机化学》 《物理化学》 | ||||||||
课程简介 | 大学化学实验不仅是传授知识、验证理论和掌握实验技能，更重要的是培养学生严谨的科学态度、严肃认真的工作作风和良好的化学素质，重在提高学生的能力，使学生能够运用所学知识解决实际问题，培养学生动手、观察、思考和表达的能力，提高学生的创新能力。 | ||||||||
建议教材 | 柯以侃等《大学化学实验》第二版，北京：化学工业出版社，2010年8月 | ||||||||
参 考 书 | 《无机化学》 《分析化学》《有机化学》 《物理化学》《大学化学实验》 | ||||||||
二、课程教育目标
化学是一门实验性很强的科学，化学实验不仅是化学理论的源泉，也是化工工程技术的基础。因此，化学实验课程是高等学校工科（化工类）学生必不可少的必修课。科学技术的综合化、整体化趋势，要求学生系统掌握完整的化学实验知识，提高分析、综合、创新的能力。《大学化学实验》以化学实验基本操作技能训练、基础化学实验、综合化学实验和设计实验构筑实验课程体系，按多层次的能力培养要求重组课程内容，以适应新世纪发展对人才培养的要求。
大学化学实验不仅是传授知识、验证理论和掌握实验技能，更重要的是培养学生严谨的科学态度、严肃认真的工作作风和良好的化学素质，重在提高学生的能力，使学生能够运用所学知识解决实际问题，培养学生动手、观察、思考和表达的能力，提高学生的创新能力。化学实验教学中心遵循“加强基本训练、着重能力培养、培养创新精神”的原则，融传授知识、培养能力和提高素质为一体，在实验教学中要求学生掌握化学研究的一般方法，重视基本操作技术，提高学生分析问题和解决问题的能力，尤其要鼓励创新，重视创新能力、实践能力、学习能力的培养。
三、理论教学与实践教学内容与要求
《有机化学实验(II)》
（48学时，1.5学分）
实验一 乙酸异戊酯的制备及结构鉴定（8学时）
了解羧酸酯常用的制备方法；掌握乙酸异戊酯的制备原理和操作；进一步掌握红外光谱仪的使用。
实验二 从茶叶中提取咖啡因（8学时）
了解通过连续萃取从茶叶中提取咖啡因的方法；掌握脂肪提取器的使用方法；学习用简单升华操作来提纯固体有机化合物。
实验三 甲基橙的制备（4学时）
学习重氮盐制备技术，了解重氮盐的控制条件；掌握和了解重氮盐偶联反应的条件，掌握甲基橙制备的原理及实验方法；进一步掌握重结晶等基本操作。
实验四 肉桂酸的制备及结构鉴定（12学时）
了解减压蒸馏的基本原理，掌握减压蒸馏的操作和应用；了解Perkin反应制备芳基取代的α,β-不饱和酸的方法；了解水蒸气蒸馏的原理，掌握水蒸气蒸馏的操作；学习无水条件下的实验操作。
实验五 薄层色谱和柱色谱（8学时）
了解色谱法的原理及其应用；学习掌握薄层色谱的实验操作技能；学习掌握柱色谱法的实验操作技能。
实验六 乙酰乙酸乙酯的制备及性质试验（8学时）
了解 Claisen酯缩合反应的机理和应用；掌握在酯缩合反应中金属钠的正确操作步骤及其应用；进一步掌握液体干燥和减压蒸馏操作。
四、作业
每个实验结束后，学生要完成实验报告，在下次实验时交给老师。
五、考核方式及成绩评定
平时成绩占70％,其中预习报告为10％，实验操作占50％，实验报告10％；
期末实验操作考核成绩占30％。
张丽丹 李顺来
2016年10月26日
化学实验教学中心
Beijing University of Chemical Technology
Syllabus for __ Experiments of OrganicChemistry A (II)
Ⅰ. General Information
Course Code ( if applied ) | CHM13101L | ||||||||
Course Information ( for new course only ) | Academic Discipline | Chemistry | Knowledge Domain | Organic Chemistry | |||||
Total Class Hours | 48 | Credits | 1.5 | Lecture Hours | Laboratory Hours | 48 | Computer Lab Hours | ||
Course Title (in Chinese) | 有机化学实验A (II) | ||||||||
Course Title (in English) | Experiments of Organic Chemistry A (II) | ||||||||
Applicable Majors | Applied Chemistry, Science Development Class | ||||||||
Semester Available | □ Spring □ Autumn □ Summer | ||||||||
Prerequisites (Course Title) | 《Inorganic Chemistry》《Analytical Chemistry》 | ||||||||
Corequisites (Course Title) | 《Organic Chemistry》 《Physical Chemistry》 | ||||||||
Brief Course Description | Experiments of Chemistry is not only meant to impart knowledge, but also to help students verify the theory and master the skills of experiment. What's more important, this course aims to help students develop the rigorous scientific attitude, serious style of work and good chemical quality with emphasis on improving students' abilities, especially the abilities of innovation. | ||||||||
Textbooks Recommended | Yikan Ke,etc，College Chemical Experiments (Second edition)，Chemical Industrial Press, Beijing，2010. | ||||||||
References | 《Inorganic Chemistry》《Analytical Chemistry》 《Organic Chemistry》 《Physical Chemistry》《Experiments of Chemistry》 | ||||||||
Ⅱ. Teaching Objectives
Chemistry is a highly experimental science, while chemistry experiments are not only a source of chemical theory, is also the basis of the chemical engineering and technology. Therefore, the courses of chemistry experiments are compulsory courses for colleges of engineering (esp. For Chemical Engineering majors). With the integration and systematic trend of science and technology, it is necessary that students grasp the systematic knowledge of chemistry experiments and improve their capabilities of analysis, synthesis, and innovation. The course is based on basic skill training of the chemical experiments, comprehensive chemical experiments and designing experiments. It reorganizes the course content to adapt to the requirements of the new century on the multi-level development of personnel.
Experiments of Chemistry is not only meant to impart knowledge, but also to help students verify the theory and master the skills of experiment. What's more important, this course aims to help students develop the rigorous scientific attitude, serious style of work and good chemical quality with emphasis on improving students' abilities, especially the abilities of innovation. The Chemical Experiment Teaching Center follows the rule of "strengthening basic training, focusing on capacity-building, and cultivating the spirit of innovation", combining the impartation of knowledge, capacity building and quality improvement as a whole. The center also puts emphasis on basic operating techniques of experiment, the abilities to analyze problems and solve problems, and in particular, it encourages students' innovation, practical ability and learning ability.
Ⅲ. Teaching Content and Requirements for the Lecturing Part andPractical Part
Experiments of OrganicChemistry (II)
(Total Course Hours:48hours，Credits:1.5)
Experiment 1. Preparation and structure identification of isoamyl acetate (8 hours)
Understand the common methods for preparing carboxylic acid ester. Learn the principles and operations of synthesizing isoamyl acetate. Further grasp the usage of infrared spectrometer.
Experiment 2. Extraction of caffeine from tea leaves (8 hours)
Understand the methods of extraction of caffeine from tea leaves by continuous extraction. Grasp the usage of Soxhlet extraction system. Learn to purify solid compounds with simple sublimation operations.
Experiment 3. Preparation of methyl orange (4 hours)
Learn the preparation technology of diazonium salt, understand the reaction conditions of synthesis of diazonium salts. Understand the coupling reactions of diazonium salts, grasp the principles and experimental methods of the preparation of methyl orange. Further grasp basic operations such as recrystallization.
Experiment 4. Preparation and structure identification of cinnamic acid (12 hours)
Understand the principles of Vacuum distillation, grasp the operations and applications of Vacuum distillation. Understand the synthetic methods of α,β unsaturated acid by Perkin reaction. Understand the principles of steam distillation, grasp the operations of steam distillation. Learn the experiment operations under anhydrous conditions.
Experiment 5.Thin layer chromatography and column chromatography (8 hours)
Understand the principle and application of chromatography. Learn and grasp the operation skill of thin layer chromatography experiment. Learn and grasp the operation skill of column chromatography experiment.
Experiment 6.The preparation and properties test of ethyl acetoacetate (8 hours)
Understand the reaction mechanism and application of Claisen condensation. Learn the correct operation procedure and application of sodium metal in the reaction of ester condensation. Further grasp the fluid drying and vacuum distillation operation.
Ⅳ. Assignments
After finishing every experiment, students are required to finish the experiment reports and hand in the reports to the teacher in the next experiment.
Ⅴ. Grading and Assessment
Formative assessment 70%: preview 10%, experiment 50%, the experiment report 10%.
Summative assessment 30%: final examination
Ⅵ. Author
Zhang Lidan Li Shunlai
2016.10.26